Genome-wide association study of primary open angle glaucoma risk and quantitative traits.
Gibson J, Griffiths H, De Salvo G et al.
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Abstract
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Purpose: Primary open angle glaucoma (POAG) is a characteristic optic neuropathy which progresses to irreversible vision loss. Few genes have been detected that influence POAG susceptibility and other genes are therefore likely to be involved. We analyzed carefully characterized POAG cases in a genome-wide association study (GWAS).
387 European ancestry cases, 5,380 European ancestry controls
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