Identification of a candidate gene for astigmatism.
Lopes MC, Hysi PG, Verhoeven VJ et al.
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Abstract
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Purpose: Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and environmental factors. Twin studies of astigmatism have found approximately 60% of phenotypic variance is explained by genetic factors. This study aimed to identify susceptibility loci for astigmatism.
22,100 European ancestry individuals
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