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GWAS Study

Genome-wide association study on differentiated thyroid cancer.

Köhler A, Chen B, Gemignani F et al.

23894154 PubMed ID
GWAS Study Type
7872 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KA
Köhler A
CB
Chen B
GF
Gemignani F
ER
Elisei R
RC
Romei C
FG
Figlioli G
CM
Cipollini M
CA
Cristaudo A
BF
Bambi F
HP
Hoffmann P
HS
Herms S
KM
Kalemba M
KD
Kula D
HS
Harris S
BP
Broderick P
HR
Houlston R
PS
Pastor S
MR
Marcos R
VA
Velázquez A
JB
Jarzab B
HK
Hemminki K
LS
Landi S
FA
Försti A
Chapter II

Abstract

Summary of the research findings

Context: Genome-wide association studies (GWASs) of differentiated thyroid cancer (DTC) have identified associations with polymorphisms at 2q35 (DIRC3), 8p12 (NRG1), 9q22.33 (FOXE1), and 14q13.2 (NKX2-1). However, most of the inherited genetic risk factors of DTC remain to be discovered.

690 European ancestry cases, 497 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

7872
Total Participants
GWAS
Study Type
Yes
Replicated
2,958 European ancestry cases, 3,727 European ancestry controls
Replication Participants
European
Ancestry
Italy, Poland, U.K., Spain
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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