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GWAS Study

Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.

Manichaikul A, Hoffman EA, Smolonska J et al.

24383474 PubMed ID
GWAS Study Type
13937 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MA
Manichaikul A
HE
Hoffman EA
SJ
Smolonska J
GW
Gao W
CM
Cho MH
BH
Baumhauer H
BM
Budoff M
AJ
Austin JH
WG
Washko GR
CJ
Carr JJ
KJ
Kaufman JD
PT
Pottinger T
PC
Powell CA
WC
Wijmenga C
ZP
Zanen P
GH
Groen HJ
PD
Postma DS
WA
Wanner A
RF
Rouhani FN
BM
Brantly ML
PR
Powell R
SB
Smith BM
RD
Rabinowitz D
RL
Raffel LJ
HS
Hinckley Stukovsky KD
CJ
Crapo JD
BT
Beaty TH
HJ
Hokanson JE
SE
Silverman EK
DJ
Dupuis J
OG
O'Connor GT
BH
Boezen HM
RS
Rich SS
BR
Barr RG
Chapter II

Abstract

Summary of the research findings

Rationale: Pulmonary emphysema overlaps partially with spirometrically defined chronic obstructive pulmonary disease and is heritable, with moderately high familial clustering.

2,587 European ancestry individuals, 2,510 African American individuals, 2,113 Hispanic individuals, 704 Chinese ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

13937
Total Participants
GWAS
Study Type
Yes
Replicated
6,023 European ancestry individuals
Replication Participants
European, East Asian, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.