A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
Wolf EJ, Rasmusson AM, Mitchell KS et al.
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Abstract
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Recent work suggests that a subset of individuals with posttraumatic stress disorder (PTSD) exhibit marked dissociative symptoms, as defined by derealization and depersonalization. A dissociative subtype of PTSD was added to the diagnostic criteria listed in the Diagnostic and Statistical Manual of Mental Disorders, Version 5 (DSM-5) to capture this presentation of PTSD. This study examined genetic polymorphisms for association with the symptoms that define the dissociative subtype of PTSD using a genome-wide approach.
484 European ancestry trauma-exposed individuals
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