Menu
GWAS Study

A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

Barnett GC, Thompson D, Fachal L et al.

24785509 PubMed ID
GWAS Study Type
3506 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BG
Barnett GC
TD
Thompson D
FL
Fachal L
KS
Kerns S
TC
Talbot C
ER
Elliott RM
DL
Dorling L
CC
Coles CE
DD
Dearnaley DP
RB
Rosenstein BS
VA
Vega A
SP
Symonds P
YJ
Yarnold J
BC
Baynes C
MK
Michailidou K
DJ
Dennis J
TJ
Tyrer JP
WJ
Wilkinson JS
GA
Gómez-Caamaño A
TG
Tanteles GA
PR
Platte R
MR
Mayes R
CD
Conroy D
MM
Maranian M
LC
Luccarini C
GS
Gulliford SL
SM
Sydes MR
HE
Hall E
HJ
Haviland J
MV
Misra V
TJ
Titley J
BS
Bentzen SM
PP
Pharoah PD
BN
Burnet NG
DA
Dunning AM
WC
West CM
Chapter II

Abstract

Summary of the research findings

Background and purpose: This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy.

579 European ancestry prostate cancer cases, 1,194 European ancestry breast cancer cases

Chapter III

Study Statistics

Key metrics and study information

3506
Total Participants
GWAS
Study Type
Yes
Replicated
516 European ancestry prostate cancer cases, 862 prostate cancer cases, 355 breast cancer cases
Replication Participants
European
Ancestry
Spain, U.S., U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.