A genome-wide association meta-analysis of preschool internalizing problems.
Benke KS, Nivard MG, Velders FP et al.
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Abstract
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Objective: Preschool internalizing problems (INT) are highly heritable and moderately genetically stable from childhood into adulthood. Gene-finding studies are scarce. In this study, the influence of genome-wide measured single nucleotide polymorphisms (SNPs) was investigated in 3 cohorts (total N = 4,596 children) in which INT was assessed with the same instrument, the Child Behavior Checklist (CBCL).
3,121 European ancestry individuals, 1,475 children from 1,031 families
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