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GWAS Study

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study.

Akerblom A, Eriksson N, Wallentin L et al.

24952865 PubMed ID
GWAS Study Type
9978 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AA
Akerblom A
EN
Eriksson N
WL
Wallentin L
SA
Siegbahn A
BB
Barratt BJ
BR
Becker RC
BA
Budaj A
HA
Himmelmann A
HS
Husted S
SR
Storey RF
JA
Johansson A
JS
James SK
Chapter II

Abstract

Summary of the research findings

Purpose: Elevated cystatin C concentration is an independent risk factor for cardiovascular (CV) events in patients with acute coronary syndromes. Genetic polymorphisms in CST3 influence cystatin C levels, but their relationship to outcomes is unclear.

9,801 European ancestry cases, 57 Black cases, 90 Oriental ancestry cases, 30 cases

Chapter III

Study Statistics

Key metrics and study information

9978
Total Participants
GWAS
Study Type
No
Replicated
European, African unspecified, Asian unspecified
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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