Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.
Kapoor M, Wang JC, Wetherill L et al.
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Abstract
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The age at onset of alcohol dependence (AD) is a critical moderator of genetic associations for alcohol dependence. The present study evaluated whether single nucleotide polymorphisms (SNPs) can influence the age at onset of AD in large high-risk families from the Collaborative Study on the Genetics of Alcoholism (COGA).
685 European ancestry cases, 1,103 European ancestry controls from 118 families
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