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GWAS Study

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.

Foroud T, Lai D, Koller D et al.

25256182 PubMed ID
GWAS Study Type
12002 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FT
Foroud T
LD
Lai D
KD
Koller D
VH
Van't Hof F
KM
Kurki MI
AC
Anderson CS
BR
Brown RD
CE
Connolly ES
EJ
Eriksson JG
FM
Flaherty M
FM
Fornage M
VU
von Und Zu Fraunberg M
GE
Gaál EI
LA
Laakso A
HJ
Hernesniemi J
HJ
Huston J
JJ
Jääskeläinen JE
KL
Kiemeney LA
KR
Kivisaari R
KD
Kleindorfer D
KN
Ko N
LH
Lehto H
MJ
Mackey J
MI
Meissner I
MC
Moomaw CJ
MT
Mosley TH
MM
Moskala M
NM
Niemelä M
PA
Palotie A
PJ
Pera J
RG
Rinkel G
RS
Ripke S
RG
Rouleau G
RY
Ruigrok Y
SL
Sauerbeck L
SA
Słowik A
VS
Vermeulen SH
WD
Woo D
WB
Worrall BB
BJ
Broderick J
Chapter II

Abstract

Summary of the research findings

Background and purpose: Common variants have been identified using genome-wide association studies which contribute to intracranial aneurysms (IA) susceptibility. However, it is clear that the variants identified to date do not account for the estimated genetic contribution to disease risk.

2,617 European ancestry cases, 2,548 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

12002
Total Participants
GWAS
Study Type
Yes
Replicated
1,516 European ancestry cases, 5,321 European ancestry controls
Replication Participants
European
Ancestry
Finland, Netherlands, U.S., Poland, Australia, New Zealand
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.