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GWAS Study

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.

Beecham GW, Dickson DW, Scott WK et al.

25663231 PubMed ID
GWAS Study Type
1629 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BG
Beecham GW
DD
Dickson DW
SW
Scott WK
ME
Martin ER
SG
Schellenberg G
NK
Nuytemans K
LE
Larson EB
BJ
Buxbaum JD
TJ
Trojanowski JQ
VD
Van Deerlin VM
HH
Hurtig HI
MD
Mash DC
BT
Beach TG
TJ
Troncoso JC
PO
Pletnikova O
FM
Frosch MP
GB
Ghetti B
FT
Foroud TM
HL
Honig LS
MK
Marder K
VJ
Vonsattel JP
GS
Goldman SM
VH
Vinters HV
RO
Ross OA
WZ
Wszolek ZK
WL
Wang L
DD
Dykxhoorn DM
PM
Pericak-Vance MA
MT
Montine TJ
LJ
Leverenz JB
DT
Dawson TM
VJ
Vance JM
Chapter II

Abstract

Summary of the research findings

Objective: To minimize pathologic heterogeneity in genetic studies of Parkinson disease (PD), the Autopsy-Confirmed Parkinson Disease Genetics Consortium conducted a genome-wide association study using both patients with neuropathologically confirmed PD and controls.

484 European ancestry cases, 1,145 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1629
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.