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GWAS Study

Genome-wide association study of perioperative myocardial infarction after coronary artery bypass surgery.

Kertai MD, Li YJ, Li YW et al.

25948407 PubMed ID
GWAS Study Type
2055 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KM
Kertai MD
LY
Li YJ
LY
Li YW
JY
Ji Y
AJ
Alexander J
NM
Newman MF
SP
Smith PK
JD
Joseph D
MJ
Mathew JP
PM
Podgoreanu MV
Chapter II

Abstract

Summary of the research findings

Objectives: Identification of patient subpopulations susceptible to develop myocardial infarction (MI) or, conversely, those displaying either intrinsic cardioprotective phenotypes or highly responsive to protective interventions remain high-priority knowledge gaps. We sought to identify novel common genetic variants associated with perioperative MI in patients undergoing coronary artery bypass grafting using genome-wide association methodology.

112 cases, 1,321 controls

Chapter III

Study Statistics

Key metrics and study information

2055
Total Participants
GWAS
Study Type
Yes
Replicated
113 European ancestry cases, 509 European ancestry controls
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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