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GWAS Study

Genome-wide association study of susceptibility loci for breast cancer in Sardinian population.

Palomba G, Loi A, Porcu E et al.

25956309 PubMed ID
GWAS Study Type
127038 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PG
Palomba G
LA
Loi A
PE
Porcu E
CA
Cossu A
ZI
Zara I
BM
Budroni M
DM
Dei M
LS
Lai S
MA
Mulas A
ON
Olmeo N
IM
Ionta MT
AF
Atzori F
CG
Cuccuru G
PM
Pitzalis M
ZM
Zoledziewska M
ON
Olla N
LM
Lovicu M
PM
Pisano M
AG
Abecasis GR
UM
Uda M
TF
Tanda F
MK
Michailidou K
ED
Easton DF
CS
Chanock SJ
HR
Hoover RN
HD
Hunter DJ
SD
Schlessinger D
SS
Sanna S
CL
Crisponi L
PG
Palmieri G
Chapter II

Abstract

Summary of the research findings

Despite progress in identifying genes associated with breast cancer, many more risk loci exist. Genome-wide association analyses in genetically-homogeneous populations, such as that of Sardinia (Italy), could represent an additional approach to detect low penetrance alleles.

1,367 Sardinian cases, 1,658 Sardinian controls

Chapter III

Study Statistics

Key metrics and study information

127038
Total Participants
GWAS
Study Type
Yes
Replicated
201 Sardinian cases, 1,467 Sardinian controls, 61,485 European ancestry cases, 60,860 European ancestry controls
Replication Participants
European
Ancestry
Italy
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.