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GWAS Study

Novel Genetic Loci Associated With Retinal Microvascular Diameter.

Jensen RA, Sim X, Smith AV et al.

26567291 PubMed ID
GWAS Study Type
29747 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JR
Jensen RA
SX
Sim X
SA
Smith AV
LX
Li X
JJ
Jakobsdóttir J
CC
Cheng CY
BJ
Brody JA
CM
Cotch MF
MB
Mcknight B
KR
Klein R
WJ
Wang JJ
KA
Kifley A
HT
Harris TB
LL
Launer LJ
TK
Taylor KD
KB
Klein BE
RL
Raffel LJ
LX
Li X
IM
Ikram MA
KC
Klaver CC
VD
van der Lee SJ
MU
Mutlu U
HA
Hofman A
UA
Uitterlinden AG
LC
Liu C
KA
Kraja AT
MP
Mitchell P
GV
Gudnason V
RJ
Rotter JI
BE
Boerwinkle E
VD
van Duijn CM
PB
Psaty BM
WT
Wong TY
Chapter II

Abstract

Summary of the research findings

There is increasing evidence that retinal microvascular diameters are associated with cardiovascular and cerebrovascular conditions. The shared genetic effects of these associations are currently unknown. The aim of this study was to increase our understanding of the genetic factors that mediate retinal vessel size.

14,740 European ancestry individuals, 5,113 Asian ancestry individuals, 3,345 African American individuals, 1,077 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

29747
Total Participants
GWAS
Study Type
Yes
Replicated
5,472 European ancestry individuals
Replication Participants
European, Hispanic or Latin American, African American or Afro-Caribbean, South Asian, South East Asian, East Asian
Ancestry
U.S., Singapore, Netherlands, Australia
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.