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GWAS Study

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.

Traylor M, Zhang CR, Adib-Samii P et al.

26674333 PubMed ID
GWAS Study Type
3670 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Traylor M
ZC
Zhang CR
AP
Adib-Samii P
DW
Devan WJ
PO
Parsons OE
LS
Lanfranconi S
GS
Gregory S
CL
Cloonan L
FG
Falcone GJ
RF
Radmanesh F
FK
Fitzpatrick K
KA
Kanakis A
BT
Barrick TR
MB
Moynihan B
LC
Lewis CM
BG
Boncoraglio GB
LR
Lemmens R
TV
Thijs V
SC
Sudlow C
WJ
Wardlaw J
RP
Rothwell PM
MJ
Meschia JF
WB
Worrall BB
LC
Levi C
BS
Bevan S
FK
Furie KL
DM
Dichgans M
RJ
Rosand J
MH
Markus HS
RN
Rost N
Chapter II

Abstract

Summary of the research findings

Objective: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms.

3,670 European ancestry cases

Chapter III

Study Statistics

Key metrics and study information

3670
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S., Australia, Italy, Canada, Belgium, Germany, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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