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GWAS Study

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up.

Gref A, Merid SK, Gruzieva O et al.

27901618 PubMed ID
GWAS Study Type
3322 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GA
Gref A
MS
Merid SK
GO
Gruzieva O
BS
Ballereau S
BA
Becker A
BT
Bellander T
BA
Bergström A
BY
Bossé Y
BM
Bottai M
CM
Chan-Yeung M
FE
Fuertes E
ID
Ierodiakonou D
JR
Jiang R
JS
Joly S
JM
Jones M
KM
Kobor MS
KM
Korek M
KA
Kozyrskyj AL
KA
Kumar A
LN
Lemonnier N
ME
MacIntyre E
MC
Ménard C
ND
Nickle D
OM
Obeidat M
PJ
Pellet J
SM
Standl M
SA
Sääf A
SC
Söderhäll C
TC
Tiesler CMT
VD
van den Berge M
VJ
Vonk JM
VH
Vora H
XC
Xu CJ
AJ
Antó JM
AC
Auffray C
BM
Brauer M
BJ
Bousquet J
BB
Brunekreef B
GW
Gauderman WJ
HJ
Heinrich J
KJ
Kere J
KG
Koppelman GH
PD
Postma D
CC
Carlsten C
PG
Pershagen G
ME
Melén E
Chapter II

Abstract

Summary of the research findings

Rationale: The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent and may depend on genetic factors.

454 European ancestry child cases, 1,080 European ancestry child controls

Chapter III

Study Statistics

Key metrics and study information

3322
Total Participants
GWAS
Study Type
Yes
Replicated
692 European ancestry child cases, 1,096 European ancestry child controls
Replication Participants
European
Ancestry
U.S., Canada, Sweden, Netherlands, Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.