A Genome-Wide Association Study of Vertical Cup-Disc Ratio in a Latino Population.
Nannini DR, Torres M, Chen YI et al.
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Abstract
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Purpose: Vertical cup-disc ratio (VCDR) is used as a clinical assessment measure to identify and monitor glaucomatous damage to the optic nerve. Previous genetic studies conducted in European and Asian populations have identified many loci associated with VCDR. The genetic factors in other ethnic populations, such as Latino, influencing VCDR remain to be determined. Here, we describe the first genome-wide association study (GWAS) on VCDR in Latino individuals.
3,596 Latino individuals
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