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GWAS Study

Genome-Wide Association Studies and Meta-Analyses for Congenital Heart Defects.

Agopian AJ, Goldmuntz E, Hakonarson H et al.

28468790 PubMed ID
GWAS Study Type
6457 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AA
Agopian AJ
GE
Goldmuntz E
HH
Hakonarson H
SA
Sewda A
TD
Taylor D
ML
Mitchell LE
Chapter II

Abstract

Summary of the research findings

Maternal and inherited (ie, case) genetic factors likely contribute to the pathogenesis of congenital heart defects, but it is unclear whether individual common variants confer a large risk.

483 European ancestry trios, 406 European ancestry cases, 2,976 European ancestry controls, 355 European and other ancestry trios, 187 non-European ancestry trios.

Chapter III

Study Statistics

Key metrics and study information

6457
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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