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GWAS Study

Genome-Wide Association Study of MKI67 Expression and its Clinical Implications in HBV-Related Hepatocellular Carcinoma in Southern China.

Yang CK, Yu TD, Han CY et al.

28700999 PubMed ID
GWAS Study Type
292 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YC
Yang CK
YT
Yu TD
HC
Han CY
QW
Qin W
LX
Liao XW
YL
Yu L
LX
Liu XG
ZG
Zhu GZ
SH
Su H
LS
Lu SC
CZ
Chen ZW
LZ
Liu Z
HK
Huang KT
LZ
Liu ZT
LY
Liang Y
HJ
Huang JL
MZ
Mo ZN
QX
Qin X
LL
Li L
XK
Xiao KY
PM
Peng MH
WC
Winkle CA
OS
O'Brien SJ
PT
Peng T
Chapter II

Abstract

Summary of the research findings

Background/aims: Hepatocellular carcinoma (HCC) is a common malignant tumor with a high rate of recurrence. Immunohistochemical analysis of the marker of proliferation Ki-67 (MKI67) is used to assess proliferation activity of HCC The regulation of MKI67 expression remains unclear in HCC This study aims to explore the association between MKI67 expression and gene variants.

195 Han Chinese ancestry cases

Chapter III

Study Statistics

Key metrics and study information

292
Total Participants
GWAS
Study Type
Yes
Replicated
97 Han Chinese ancestry cases
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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