Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.
Christophersen IE, Magnani JW, Yin X et al.
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Abstract
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The P wave on an ECG is a measure of atrial electric function, and its characteristics may serve as predictors for atrial arrhythmias. Increased mean P-wave duration and P-wave terminal force traditionally have been used as markers for left atrial enlargement, and both have been associated with increased risk of atrial fibrillation. Here, we explore the genetic basis of P-wave morphology through meta-analysis of genome-wide association study results for P-wave duration and P-wave terminal force from 12 cohort studies.
33,955 European ancestry individuals, 6,778 African individuals
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