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GWAS Study

Novel Susceptibility Loci for Moyamoya Disease Revealed by a Genome-Wide Association Study.

Duan L, Wei L, Tian Y et al.

29273593 PubMed ID
GWAS Study Type
6553 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DL
Duan L
WL
Wei L
TY
Tian Y
ZZ
Zhang Z
HP
Hu P
WQ
Wei Q
LS
Liu S
ZJ
Zhang J
WY
Wang Y
LD
Li D
YW
Yang W
ZR
Zong R
XP
Xian P
HC
Han C
BX
Bao X
ZF
Zhao F
FJ
Feng J
LW
Liu W
CW
Cao W
ZG
Zhou G
ZC
Zhu C
YF
Yu F
YW
Yang W
MY
Meng Y
WJ
Wang J
CX
Chen X
WY
Wang Y
SB
Shen B
ZB
Zhao B
WJ
Wan J
ZF
Zhang F
ZG
Zhao G
XA
Xu A
ZX
Zhang X
LJ
Liu J
ZX
Zuo X
WK
Wang K
Chapter II

Abstract

Summary of the research findings

Background and purpose: Moyamoya disease (MMD) is a rare cerebral vasculopathy characterized by bilateral internal carotid artery stenosis and often leads to stroke in children or young adults. Although familial inheritance is well recognized, the genetic basis of MMD remains poorly understood.

755 Han Chinese ancestry cases, 2,031 Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6553
Total Participants
GWAS
Study Type
Yes
Replicated
724 Han Chinese ancestry cases, 3,043 Han Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.