Menu
GWAS Study

A novel variant in GLIS3 is associated with osteoarthritis.

Casalone E, Tachmazidou I, Zengini E et al.

29436472 PubMed ID
GWAS Study Type
122717 Participants
Scroll to explore
Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CE
Casalone E
TI
Tachmazidou I
ZE
Zengini E
HK
Hatzikotoulas K
HS
Hackinger S
SD
Suveges D
SJ
Steinberg J
RN
Rayner NW
WJ
Wilkinson JM
PK
Panoutsopoulou K
ZE
Zeggini E
Chapter II

Abstract

Summary of the research findings

Objectives: Osteoarthritis (OA) is a complex disease, but its genetic aetiology remains poorly characterised. To identify novel susceptibility loci for OA, we carried out a genome-wide association study (GWAS) in individuals from the largest UK-based OA collections to date.

5,414 European ancestry cases, 9,939 European ancestry healthy controls

Chapter III

Study Statistics

Key metrics and study information

122717
Total Participants
GWAS
Study Type
Yes
Replicated
17,894 European ancestry cases, 89,470 European ancestry healthy controls
Replication Participants
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.