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GWAS Study

Host genetic susceptibility to Clostridium difficile infections in patients undergoing autologous stem cell transplantation: a genome-wide association study.

Apewokin S, Lee JY, Goodwin JA et al.

29594489 PubMed ID
GWAS Study Type
646 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

AS
Apewokin S
LJ
Lee JY
GJ
Goodwin JA
MK
McKelvey KD
SO
Stephens OW
ZD
Zhou D
CE
Coleman EA
Chapter II

Abstract

Summary of the research findings

Clostridium difficile infection (CDI) is the most common hospital-acquired infection. Unfortunately, genes that identify CDI-susceptible patients have not been well described. We performed a genome-wide association study (GWAS) to determine genetic variants associated with the development of CDI.

57 European ancestry cases, 589 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

646
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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