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GWAS Study

Genome-wide association study: Exploring the genetic basis for responsiveness to ketogenic dietary therapies for drug-resistant epilepsy.

Schoeler NE, Leu C, Balestrini S et al.

30009487 PubMed ID
GWAS Study Type
235 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

SN
Schoeler NE
LC
Leu C
BS
Balestrini S
MJ
Mudge JM
SC
Steward CA
FA
Frankish A
LM
Leung MA
MM
Mackay M
SI
Scheffer I
WR
Williams R
SJ
Sander JW
CJ
Cross JH
SS
Sisodiya SM
Chapter II

Abstract

Summary of the research findings

Objective: With the exception of specific metabolic disorders, predictors of response to ketogenic dietary therapies (KDTs) are unknown. We aimed to determine whether common variation across the genome influences the response to KDT for epilepsy.

123 responders, 112 non-responders

Chapter III

Study Statistics

Key metrics and study information

235
Total Participants
GWAS
Study Type
No
Replicated
Australia, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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