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GWAS Study

Variation at the TRIM11 locus modifies Progressive Supranuclear Palsy phenotype.

Jabbari E, Woodside J, Tan MMX et al.

30066433 PubMed ID
GWAS Study Type
497 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JE
Jabbari E
WJ
Woodside J
TM
Tan MMX
SM
Shoai M
PA
Pittman A
FR
Ferrari R
MK
Mok KY
ZD
Zhang D
RR
Reynolds RH
DS
de Silva R
GM
Grimm MJ
RG
Respondek G
MU
Müller U
AS
Al-Sarraj S
GS
Gentleman SM
LA
Lees AJ
WT
Warner TT
HJ
Hardy J
RT
Revesz T
HG
Höglinger GU
HJ
Holton JL
RM
Ryten M
MH
Morris HR
Chapter II

Abstract

Summary of the research findings

Objective: The basis for clinical variation related to underlying progressive supranuclear palsy (PSP) pathology is unknown. We performed a genome-wide association study (GWAS) to identify genetic determinants of PSP phenotype.

130 European ancestry non-Richardson's syndrome cases, 367 European ancestry Richardson's syndrome controls

Chapter III

Study Statistics

Key metrics and study information

497
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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