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GWAS Study

Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.

Galván-Femenía I, Obón-Santacana M, Piñeyro D et al.

30166351 PubMed ID
GWAS Study Type
341095 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GI
Galván-Femenía I
OM
Obón-Santacana M
PD
Piñeyro D
GM
Guindo-Martinez M
DX
Duran X
CA
Carreras A
PR
Pluvinet R
VJ
Velasco J
RL
Ramos L
AS
Aussó S
MJ
Mercader JM
PL
Puig L
PM
Perucho M
TD
Torrents D
MV
Moreno V
SL
Sumoy L
DC
de Cid R
Chapter II

Abstract

Summary of the research findings

Heritability estimates have revealed an important contribution of SNP variants for most common traits; however, SNP analysis by single-trait genome-wide association studies (GWAS) has failed to uncover their impact. In this study, we applied a multitrait GWAS approach to discover additional factor of the missing heritability of human anthropometric variation.

4,988 Spanish ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

341095
Total Participants
GWAS
Study Type
Yes
Replicated
336,107 British ancestry individuals
Replication Participants
European
Ancestry
Spain, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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