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GWAS Study

GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

Heinzman JT, Hoth KF, Cho MH et al.

30219690 PubMed ID
GWAS Study Type
9716 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HJ
Heinzman JT
HK
Hoth KF
CM
Cho MH
SP
Sakornsakolpat P
RE
Regan EA
MB
Make BJ
KG
Kinney GL
WF
Wamboldt FS
HK
Holm KE
BN
Bormann N
RJ
Robles J
KV
Kim V
IA
Iyer AS
SE
Silverman EK
CJ
Crapo JD
HS
Han S
PJ
Potash JB
SG
Shinozaki G
Chapter II

Abstract

Summary of the research findings

Large sample GWAS is needed to identify genetic factors associated with depression. This study used genome-wide genotypic and phenotypic data from the COPDGene study to identify genetic risk factors for depression.

1,622 European ancestry cases, 391 African American cases, 4,954 European ancestry controls, 2,749 African American controls

Chapter III

Study Statistics

Key metrics and study information

9716
Total Participants
GWAS
Study Type
No
Replicated
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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