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GWAS Study

Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study.

Brouwer WP, Chan HLY, Lampertico P et al.

30715261 PubMed ID
GWAS Study Type
414 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BW
Brouwer WP
CH
Chan HLY
LP
Lampertico P
HJ
Hou J
TP
Tangkijvanich P
RH
Reesink HW
ZW
Zhang W
MA
Mangia A
TT
Tanwandee T
MG
Montalto G
SK
Simon K
ON
Ormeci N
CL
Chen L
TF
Tabak F
GF
Gunsar F
FR
Flisiak R
FP
Ferenci P
AM
Akdogan M
AF
Akyuz F
HN
Hirankarn N
JL
Jansen L
WV
Wong VW
SR
Soffredini R
LX
Liang X
CS
Chen S
GZ
Groothuismink ZMA
SR
Santoro R
JJ
Jaroszewicz J
OR
Ozaras R
KK
Kozbial K
BM
Brahmania M
XQ
Xie Q
CW
Chotiyaputta W
XQ
Xun Q
PM
Pazgan-Simon M
OE
Oztas E
VE
Verhey E
MN
Montanari NR
SJ
Sun J
HB
Hansen BE
BA
Boonstra A
JH
Janssen HLA
Chapter II

Abstract

Summary of the research findings

(Pegylated) Interferon ([Peg]IFN) therapy leads to response in a minority of chronic hepatitis B (CHB) patients. Host genetic determinants of response are therefore in demand.

161 Asian, European, African and other ancestry cases, 253 Asian, European, African and other ancestry controls

Chapter III

Study Statistics

Key metrics and study information

414
Total Participants
GWAS
Study Type
No
Replicated
European, African unspecified, Asian unspecified, NR
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.