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GWAS Study

Genome-Wide Association Scan of Serum Urea in European Populations Identifies Two Novel Loci.

Thio CHL, Reznichenko A, van der Most PJ et al.

30808845 PubMed ID
GWAS Study Type
20691 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TC
Thio CHL
RA
Reznichenko A
VD
van der Most PJ
KZ
Kamali Z
VA
Vaez A
SJ
Smit JH
PB
Penninx BWJH
HT
Haller T
ME
Mihailov E
MA
Metspalu A
DJ
Damman J
DB
de Borst MH
VD
van der Harst P
VN
Verweij N
NG
Navis GJ
GR
Gansevoort RT
NI
Nolte IM
SH
Snieder H
Chapter II

Abstract

Summary of the research findings

Serum urea level is a heritable trait, commonly used as a diagnostic marker for kidney function. Genome-wide association studies (GWAS) in East-Asian populations identified a number of genetic loci related to serum urea, however there is a paucity of data for European populations.

13,312 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

20691
Total Participants
GWAS
Study Type
Yes
Replicated
7,379 European ancestry individuals
Replication Participants
European
Ancestry
Netherlands
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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