Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations.
Wang Y, Karstoft KI, Nievergelt CM et al.
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Abstract
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Post-traumatic stress disorder (PTSD) is a complex psychiatric disorder that occurs with relatively high frequency after deployment to warzones (∼10%). While twin studies have estimated the heritability to be up to 40%, thus indicating a considerable genetic component in the etiology, the biological mechanisms underlying risk and development of PTSD remain unknown.
462 Danish ancestry cases, 2,019 Danish ancestry controls
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