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GWAS Study

Assessment of Molecular Subtypes in Thyrotoxic Periodic Paralysis and Graves Disease Among Chinese Han Adults: A Population-Based Genome-Wide Association Study.

Zhao SX, Liu W, Liang J et al.

31050781 PubMed ID
GWAS Study Type
1575 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

ZS
Zhao SX
LW
Liu W
LJ
Liang J
GG
Gao GQ
ZX
Zhang XM
YY
Yao Y
WH
Wang HN
YF
Yuan FF
XL
Xue LQ
MY
Ma YR
ZL
Zhang LL
YX
Ye XP
ZQ
Zhang QY
SF
Sun F
ZR
Zhang RJ
YS
Yang SY
ZM
Zhan M
DW
Du WH
LB
Liu BL
CX
Chen X
SZ
Song ZY
LX
Li XS
LP
Li P
RY
Ru Y
ZC
Zuo CL
LS
Li SX
HB
Han B
ZH
Zhu H
QJ
Qiao J
XM
Xuan M
SB
Su B
SF
Sun F
MJ
Ma JH
CJ
Chen JL
TH
Tian HM
CS
Chen SJ
SH
Song HD
Chapter II

Abstract

Summary of the research findings

Importance: Thyrotoxic periodic paralysis (TPP) is a potentially lethal complication of hyperthyroidism. However, only 1 specific susceptibility locus for TPP has been identified. Additional genetic determinants should be detected so that a prediction model can be constructed.

171 Han Chinese ancestry cases with TPP, 1,404 Han Chinese ancestry cases without TPP

Chapter III

Study Statistics

Key metrics and study information

1575
Total Participants
GWAS
Study Type
Yes
Replicated
362 Han Chinese ancestry cases, 1,089 Han Chinese ancestry controls
Replication Participants
East Asian
Ancestry
China
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.