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GWAS Study

Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study.

Khawaja AP, Rojas Lopez KE, Hardcastle AJ et al.

31246245 PubMed ID
GWAS Study Type
9029 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KA
Khawaja AP
RL
Rojas Lopez KE
HA
Hardcastle AJ
HC
Hammond CJ
LP
Liskova P
DA
Davidson AE
GD
Gore DM
HT
Hafford Tear NJ
PN
Pontikos N
HS
Hayat S
WN
Wareham N
KK
Khaw KT
TS
Tuft SJ
FP
Foster PJ
HP
Hysi PG
Chapter II

Abstract

Summary of the research findings

Importance: Keratoconus is an important cause of visual loss in young adults, but little is known about its genetic causes. Understanding the genetic determinants of corneal biomechanical factors may in turn teach us about keratoconus etiology.

6,645 individuals

Chapter III

Study Statistics

Key metrics and study information

9029
Total Participants
GWAS
Study Type
Yes
Replicated
2,384 European ancestry individuals
Replication Participants
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.