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GWAS Study

Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.

Kawamura Y, Nakaoka H, Nakayama A et al.

31289104 PubMed ID
GWAS Study Type
6009 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KY
Kawamura Y
NH
Nakaoka H
NA
Nakayama A
OY
Okada Y
YK
Yamamoto K
HT
Higashino T
SM
Sakiyama M
ST
Shimizu T
OH
Ooyama H
OK
Ooyama K
NM
Nagase M
HY
Hidaka Y
SY
Shirahama Y
HK
Hosomichi K
NY
Nishida Y
SI
Shimoshikiryo I
HA
Hishida A
KS
Katsuura-Kamano S
SS
Shimizu S
KM
Kawaguchi M
UH
Uemura H
IR
Ibusuki R
HM
Hara M
NM
Naito M
TM
Takao M
NM
Nakajima M
IS
Iwasawa S
NH
Nakashima H
OK
Ohnaka K
NT
Nakamura T
SB
Stiburkova B
MT
Merriman TR
NM
Nakatochi M
IS
Ichihara S
YM
Yokota M
TT
Takada T
ST
Saitoh T
KY
Kamatani Y
TA
Takahashi A
AK
Arisawa K
TT
Takezaki T
TK
Tanaka K
WK
Wakai K
KM
Kubo M
HT
Hosoya T
IK
Ichida K
II
Inoue I
SN
Shinomiya N
MH
Matsuo H
Chapter II

Abstract

Summary of the research findings

Objective: The first ever genome-wide association study (GWAS) of clinically defined gout cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel gout loci that aggravate AHUA into gout.

945 Japanese ancestry cases, 1,003 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

6009
Total Participants
GWAS
Study Type
Yes
Replicated
1,915 Japanese ancestry cases, 2,146 Japanese ancestry controls
Replication Participants
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.