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GWAS Study

Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.

Lona-Durazo F, Hernandez-Pacheco N, Fan S et al.

31315583 PubMed ID
GWAS Study Type
2104 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LF
Lona-Durazo F
HN
Hernandez-Pacheco N
FS
Fan S
ZT
Zhang T
CJ
Choi J
KM
Kovacs MA
LS
Loftus SK
LP
Le P
EM
Edwards M
FC
Fortes-Lima CA
EC
Eng C
HS
Huntsman S
HD
Hu D
GE
Gómez-Cabezas EJ
ML
Marín-Padrón LC
GJ
Grauholm J
MO
Mors O
BE
Burchard EG
NH
Norton HL
PW
Pavan WJ
BK
Brown KM
TS
Tishkoff S
PM
Pino-Yanes M
BS
Beleza S
MB
Marcheco-Teruel B
PE
Parra EJ
Chapter II

Abstract

Summary of the research findings

Association studies in recently admixed populations are extremely useful to identify the genetic architecture of pigmentation, due to their high genotypic and phenotypic variation. However, to date only four Genome-Wide Association Studies (GWAS) have been carried out in these populations.

1,047 Hispanic/Latin American individuals, 684 Cape Verdian individuals, 373 African American individuals

Chapter III

Study Statistics

Key metrics and study information

2104
Total Participants
GWAS
Study Type
Yes
Replicated
East African ancestry individuals (See Crawford et. al, 2017)
Replication Participants
Hispanic or Latin American, African American or Afro-Caribbean, Other admixed ancestry, Sub-Saharan African
Ancestry
Cuba, Puerto Rico, U.S., Cape Verde
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.