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GWAS Study

Serologic, but Not Genetic, Markers Are Associated With Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease.

Naramore SK, Bennett WE, Jiang G et al.

31393333 PubMed ID
GWAS Study Type
772 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

NS
Naramore SK
BW
Bennett WE
JG
Jiang G
KS
Kugathasan S
DL
Denson LA
HJ
Hyams JS
SS
Steiner SJ
Chapter II

Abstract

Summary of the research findings

Objectives: Children with Crohn's disease may present with malnutrition and linear growth impairment, which can be secondary to insufficient caloric intake, chronic inflammation, malabsorption, and suppression of growth-promoting hormones. We evaluated clinical, serologic, and genetic data to determine risk factors for impaired anthropometrics in Crohn's disease at diagnosis.

637 European ancestry children, 46 African-American children, 29 Asian ancestry children, 60 children

Chapter III

Study Statistics

Key metrics and study information

772
Total Participants
GWAS
Study Type
No
Replicated
European, African American or Afro-Caribbean, Asian unspecified
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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