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GWAS Study

Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.

Raghavan NS, Dumitrescu L, Mormino E et al.

32568366 PubMed ID
GWAS Study Type
4314 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RN
Raghavan NS
DL
Dumitrescu L
ME
Mormino E
ME
Mahoney ER
LA
Lee AJ
GY
Gao Y
BM
Bilgel M
GD
Goldstein D
HT
Harrison T
EC
Engelman CD
SA
Saykin AJ
WC
Whelan CD
LJ
Liu JZ
JW
Jagust W
AM
Albert M
JS
Johnson SC
YH
Yang HS
JK
Johnson K
AP
Aisen P
RS
Resnick SM
SR
Sperling R
DJ
De Jager PL
SJ
Schneider J
BD
Bennett DA
SM
Schrag M
VB
Vardarajan B
HT
Hohman TJ
MR
Mayeux R
Chapter II

Abstract

Summary of the research findings

Importance: Genetic studies of Alzheimer disease have focused on the clinical or pathologic diagnosis as the primary outcome, but little is known about the genetic basis of the preclinical phase of the disease.

4,120 Europea ancestry individuals, 89 African American individuals, 105 Hispanic individuals

Chapter III

Study Statistics

Key metrics and study information

4314
Total Participants
GWAS
Study Type
No
Replicated
European, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.