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GWAS Study

Genome-wide association study identifies a novel maternal gene × stress interaction associated with spontaneous preterm birth.

Hong X, Surkan PJ, Zhang B et al.

32726798 PubMed ID
GWAS Study Type
2565 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HX
Hong X
SP
Surkan PJ
ZB
Zhang B
KA
Keiser A
JY
Ji Y
JH
Ji H
BI
Burd I
BB
Bustamante-Helfrich B
OS
Ogunwole SM
TW
Tang WY
LL
Liu L
PC
Pearson C
CS
Cerda S
ZB
Zuckerman B
HL
Hao L
WX
Wang X
Chapter II

Abstract

Summary of the research findings

Maternal stress is potentially a modifiable risk factor for spontaneous preterm birth (sPTB). However, epidemiologic findings on the maternal stress-sPTB relationship have been inconsistent.

457 African American cases, 1,033 African American controls

Chapter III

Study Statistics

Key metrics and study information

2565
Total Participants
GWAS
Study Type
Yes
Replicated
171 African American cases, 166 African American controls, 353 European ancestry cases, 385 European ancestry controls
Replication Participants
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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