Genome-Wide Association Analysis of Pancreatic Beta Cell Glucose Sensitivity.
Deshmukh HA, Madsen AL, Viñuela A et al.
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Abstract
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Context: Pancreatic beta-cell glucose sensitivity is the slope of the plasma glucose-insulin secretion relationship and is a key predictor of deteriorating glucose tolerance and development of type 2 diabetes. However, there are no large-scale studies looking at the genetic determinants of beta-cell glucose sensitivity.
3,017 European ancestry individuals
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