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GWAS Study

Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.

Klarin D, Verma SS, Judy R et al.

32981348 PubMed ID
GWAS Study Type
290118 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

KD
Klarin D
VS
Verma SS
JR
Judy R
DO
Dikilitas O
WB
Wolford BN
PI
Paranjpe I
LM
Levin MG
PC
Pan C
TC
Tcheandjieu C
SJ
Spin JM
LJ
Lynch J
AT
Assimes TL
ÅN
Åldstedt Nyrønning L
ME
Mattsson E
ET
Edwards TL
DJ
Denny J
LE
Larson E
LM
Lee MTM
CD
Carrell D
ZY
Zhang Y
JG
Jarvik GP
GA
Gharavi AG
HJ
Harley J
MF
Mentch F
PJ
Pacheco JA
HH
Hakonarson H
SA
Skogholt AH
TL
Thomas L
GM
Gabrielsen ME
HK
Hveem K
NJ
Nielsen JB
ZW
Zhou W
FL
Fritsche L
HJ
Huang J
NP
Natarajan P
SY
Sun YV
DS
DuVall SL
RD
Rader DJ
CK
Cho K
CK
Chang KM
WP
Wilson PWF
OC
O'Donnell CJ
KS
Kathiresan S
SS
Scali ST
BS
Berceli SA
WC
Willer C
JG
Jones GT
BM
Bown MJ
NG
Nadkarni G
KI
Kullo IJ
RM
Ritchie M
DS
Damrauer SM
TP
Tsao PS
Chapter II

Abstract

Summary of the research findings

Abdominal aortic aneurysm (AAA) is an important cause of cardiovascular mortality; however, its genetic determinants remain incompletely defined. In total, 10 previously identified risk loci explain a small fraction of AAA heritability.

7,642 European ancestry cases, 172,172 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

290118
Total Participants
GWAS
Study Type
Yes
Replicated
2,835 European ancestry cases, 107,469 European ancestry controls
Replication Participants
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.