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GWAS Study

Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents.

Docherty AR, Shabalin AA, DiBlasi E et al.

32998551 PubMed ID
GWAS Study Type
18223 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

DA
Docherty AR
SA
Shabalin AA
DE
DiBlasi E
ME
Monson E
MN
Mullins N
AD
Adkins DE
BS
Bacanu SA
BA
Bakian AV
CS
Crowell S
CD
Chen D
DT
Darlington TM
CW
Callor WB
CE
Christensen ED
GD
Gray D
KB
Keeshin B
KM
Klein M
AJ
Anderson JS
JL
Jerominski L
HC
Hayward C
PD
Porteous DJ
MA
McIntosh A
LQ
Li Q
CH
Coon H
Chapter II

Abstract

Summary of the research findings

Objective: Death by suicide is a highly preventable yet growing worldwide health crisis. To date, there has been a lack of adequately powered genomic studies of suicide, with no sizable suicide death cohorts available for analysis. To address this limitation, the authors conducted the first comprehensive genomic analysis of suicide death using previously unpublished genotype data from a large population-ascertained cohort.

3,413 European ancestry cases, 14,810 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

18223
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K., U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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