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GWAS Study

Genome-wide and candidate gene association analyses identify a 14-SNPs combination for hypertension in patients with type 2 diabetes.

Cheng CF, Hsieh AR, Liang WM et al.

33276381 PubMed ID
GWAS Study Type
1921 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CC
Cheng CF
HA
Hsieh AR
LW
Liang WM
CC
Chen CC
CC
Chen CH
WJ
Wu JY
LT
Lin TH
LC
Liao CC
HS
Huang SM
HY
Huang YC
BB
Ban B
LY
Lin YJ
TF
Tsai FJ
Chapter II

Abstract

Summary of the research findings

High blood pressure is common and comorbid with type 2 diabetes (T2D). Almost 50% of patients with T2D have high blood pressure. Patients with both conditions of hypertension (HTN) and T2D are at risk for cardiovascular diseases and mortality. The study aim was to investigate genetic risk factors for HTN in T2D patients.

454 Han Chinese ancestry cases, 545 Han Chinese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

1921
Total Participants
GWAS
Study Type
Yes
Replicated
563 Han Chinese ancestry cases, 359 Han Chinese ancestry controls
Replication Participants
East Asian
Ancestry
Taiwan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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