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GWAS Study

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test.

Jonsson A, Stinson SE, Torekov SS et al.

33407418 PubMed ID
GWAS Study Type
1899 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

JA
Jonsson A
SS
Stinson SE
TS
Torekov SS
CT
Clausen TD
FK
Færch K
KL
Kelstrup L
GN
Grarup N
ME
Mathiesen ER
DP
Damm P
WD
Witte DR
JM
Jørgensen ME
PO
Pedersen O
HJ
Holst JJ
HT
Hansen T
Chapter II

Abstract

Summary of the research findings

In order to explore the pathophysiology underlying type 2 diabetes we examined the impact of gene variants associated with type 2 diabetes on circulating levels of glucagon during an oral glucose tolerance test (OGTT). Furthermore, we performed a genome-wide association study (GWAS) aiming to identify novel genomic loci affecting plasma glucagon levels.

553 European ancestry individuals, 1,346 individuals

Chapter III

Study Statistics

Key metrics and study information

1899
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Denmark
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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