CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers.
Johnson N, Maguire S, Morra A et al.
Publication Details
Comprehensive information about this research publication
Authors
Abstract
Summary of the research findings
Epidemiological studies provide strong evidence for a role of endogenous sex hormones in the aetiology of breast cancer. The aim of this analysis was to identify genetic variants that are associated with urinary sex-hormone levels and breast cancer risk.
560 European ancestry individuals
Study Statistics
Key metrics and study information
Analysis
Comprehensive review of health and genetic findings
Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.
Analysis In Progress
Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.
Summary
Key Findings
Health Insights
Disease Analysis
Genetic Trait Analysis
Clinical Relevance
Scientific Assessment
Related Publications
Other publications that may be of interest
Blood metabolic biomarkers and colorectal cancer risk: results from large prospective cohort and Mendelian randomisation analyses.
Yuan F
Br J Cancer
Cholesterol percentage of total lipids in small low-density lipoprotein
A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis.
Schack LMH
Br J Cancer
Acute dysphagia (moderate to severe) in head and neck cancer treated with radiotherapy
Genome-wide association study of germline variants and breast cancer-specific mortality.
Escala-Garcia M
Br J Cancer
Breast cancer specific mortality in breast cancer
Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.
Quintanilha JCF
Br J Cancer
Bevacizumab-induced hypertension
Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100.
Schneider BP
Br J Cancer
Response to chemotherapy in breast cancer (hypertension) (bevacizumab)
Explore More Research
Discover the latest findings in health and genetic research