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GWAS Study

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

Traylor M, Persyn E, Tomppo L et al.

33773637 PubMed ID
GWAS Study Type
225419 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TM
Traylor M
PE
Persyn E
TL
Tomppo L
KS
Klasson S
AV
Abedi V
BM
Bakker MK
TN
Torres N
LL
Li L
BS
Bell S
RL
Rutten-Jacobs L
TD
Tozer DJ
GC
Griessenauer CJ
ZY
Zhang Y
PA
Pedersen A
SP
Sharma P
JJ
Jimenez-Conde J
RT
Rundek T
GR
Grewal RP
LA
Lindgren A
MJ
Meschia JF
SV
Salomaa V
HA
Havulinna A
KC
Kourkoulis C
CK
Crawford K
MS
Marini S
MB
Mitchell BD
KS
Kittner SJ
RJ
Rosand J
DM
Dichgans M
JC
Jern C
SD
Strbian D
FI
Fernandez-Cadenas I
ZR
Zand R
RY
Ruigrok Y
RN
Rost N
LR
Lemmens R
RP
Rothwell PM
AC
Anderson CD
WJ
Wardlaw J
LC
Lewis CM
MH
Markus HS
Chapter II

Abstract

Summary of the research findings

The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease.

6,030 European ancestry cases, 248,929 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

225419
Total Participants
GWAS
Study Type
No
Replicated
European, African American or Afro-Caribbean, Hispanic or Latin American
Ancestry
Netherlands, Sweden, U.S., Belgium, Finland, Poland, Italy, U.K., Australia, Germany, Spain
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.