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GWAS Study

Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study.

Williams CJ, Li Z, Harvey N et al.

33985508 PubMed ID
GWAS Study Type
546 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WC
Williams CJ
LZ
Li Z
HN
Harvey N
LR
Lea RA
GB
Gurd BJ
BJ
Bonafiglia JT
PI
Papadimitriou I
JM
Jacques M
CI
Croci I
SD
Stensvold D
WU
Wisloff U
TJ
Taylor JL
GT
Gajanand T
CE
Cox ER
RJ
Ramos JS
FR
Fassett RG
LJ
Little JP
FM
Francois ME
HC
Hearon CM
SS
Sarma S
JS
Janssen SLJE
VC
Van Craenenbroeck EM
BP
Beckers P
CV
Cornelissen VA
HE
Howden EJ
KS
Keating SE
YX
Yan X
BD
Bishop DJ
BA
Bye A
HL
Haupt LM
GL
Griffiths LR
AK
Ashton KJ
BM
Brown MA
TL
Torquati L
EN
Eynon N
CJ
Coombes JS
Chapter II

Abstract

Summary of the research findings

Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is considerable inter-individual variability in the V̇O2peak response to the same dose of exercise. Understanding how genetic factors contribute to V̇O2peak training response may improve personalisation of exercise programs. The aim of this study was to identify genetic variants that are associated with the magnitude of V̇O2peak response following exercise training.

507 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

546
Total Participants
GWAS
Study Type
Yes
Replicated
39 European ancestry individuals
Replication Participants
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.