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GWAS Study

Evaluate the effects of serum urate level on bone mineral density: a genome-wide gene-environment interaction analysis in UK Biobank cohort.

Yao Y, Chu X, Ma M et al.

34046847 PubMed ID
GWAS Study Type
237799 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YY
Yao Y
CX
Chu X
MM
Ma M
YJ
Ye J
WY
Wen Y
LP
Li P
CB
Cheng B
CS
Cheng S
ZL
Zhang L
LL
Liu L
QX
Qi X
LC
Liang C
KO
Kafle OP
WC
Wu C
WS
Wang S
WX
Wang X
NY
Ning Y
ZF
Zhang F
Chapter II

Abstract

Summary of the research findings

Introduction: Serum urate is associated with BMD and may be a protective factor. However, the exact association and mechanism are still unclear. We performed a genome-wide gene-environmental interaction study (GWGEIS) to explore the interaction effects between gene and urate on BMD, using data from the UK Biobank cohort.

110,465 men, 127,334 women

Chapter III

Study Statistics

Key metrics and study information

237799
Total Participants
GWAS
Study Type
No
Replicated
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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