Investigating Pleiotropy Between Depression and Autoimmune Diseases Using the UK Biobank.
Glanville KP, Coleman JRI, O'Reilly PF et al.
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Abstract
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Epidemiological studies report increased comorbidity between depression and autoimmune diseases. The role of shared genetic influences in the observed comorbidity is unclear. We investigated the evidence for pleiotropy between these traits in the UK Biobank (UKB).
65,075 European ancestry cases, 232,552 European ancestry controls
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