Associations between age of menarche and genetic variation in women of African descent: genome-wide association study and polygenic score analysis.
Scannell Bryan M, Ogundiran T, Ojengbede O et al.
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Abstract
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Introduction: Many diseases of adulthood are associated with a woman's age at menarche. Genetic variation affects age at menarche, but it remains unclear whether in women of African ancestry the timing of menarche is regulated by genetic variants that were identified in predominantly European and East Asian populations.
3,145 African American, African Barbadian or Nigerian ancestry individuals
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