A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population.
Wu SE, Chen WL
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Abstract
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Purpose: A genome-wide association study (GWAS) of sarcopenia unraveled the importance of genetic contribution to decline in muscle. The current study investigated sarcopenia-related single nucleotide polymorphisms (SNPs) in Asian older adults, and further constructed a genotype score that tests the combined effect of these SNPs on risk of sarcopenia.
35 Taiwanese ancestry cases, 61 Taiwanese ancestry controls
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