Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.
Yeung MW, Wang S, van de Vegte YJ et al.
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Abstract
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Objective: Carotid artery intima-media thickness (cIMT) is a widely accepted marker of subclinical atherosclerosis. Twenty susceptibility loci for cIMT were previously identified and the identification of additional susceptibility loci furthers our knowledge on the genetic architecture underlying atherosclerosis.
43,775 European ancestry individuals, 612 Asian ancestry individuals, 291 Black individuals, 215 Mixed ancestry individuals, 292 individuals
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